منابع مشابه
White Matter Lesion Progression in LADIS
Reinhold Schmidt, MD; Andrea Berghold, PhD; Hanna Jokinen, PhD; Alida A. Gouw, MD, PhD; Wiesje M. van der Flier, PhD; Frederik Barkhof, MD, PhD; Philip Scheltens, MD; Katja Petrovic, Msc; Sofia Madureira, PsyD; Ana Verdelho, MD; Jose M. Ferro, MD, PhD; Gunhild Waldemar, MD; Anders Wallin, MD; Lars-Olof Wahlund, MD; Anna Poggesi, MD; Leonardo Pantoni, MD, PhD; Domenico Inzitari, MD; Franz Fazeka...
متن کاملWhite Matter Lesion Progression: Genome-Wide Search for Genetic Influences.
BACKGROUND AND PURPOSE White matter lesion (WML) progression on magnetic resonance imaging is related to cognitive decline and stroke, but its determinants besides baseline WML burden are largely unknown. Here, we estimated heritability of WML progression, and sought common genetic variants associated with WML progression in elderly participants from the Cohorts for Heart and Aging Research in ...
متن کاملHigh blood pressure and cerebral white matter lesion progression in the general population.
High blood pressure is considered an important risk factor for cerebral white matter lesions (WMLs) in the aging population. In a longitudinal population-based study of 665 nondemented persons, we investigated the longitudinal relationship of systolic blood pressure, diastolic blood pressure, and pulse pressure with annual progression of WMLs. Means of blood pressure were calculated over a 5-ye...
متن کاملApolipoprotein E genotype is related to progression of white matter lesion load.
BACKGROUND AND PURPOSE The relationship between white matter lesions (WMLs) and the apolipoprotein E genotype has been controversial from cross-sectional studies and no longitudinal finding has been reported. We investigated whether the apolipoprotein E genotype influences baseline and evolution over 4-year follow-up of WML volumes in a population-based sample of 1779 nondemented subjects aged ...
متن کاملEnzyme replacement therapy stabilized white matter lesion progression in Fabry disease.
BACKGROUND The central nervous system manifestations in Fabry disease (FD) include progressive white matter lesions (WMLs) and stroke. Due to progressive microvascular involvement, men and women with FD over 35 years of age develop WMLs. Moreover, the prevalence of stroke has been estimated to be 12 times higher in FD compared with the general population. Enzyme replacement therapy (ERT) is ava...
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ژورنال
عنوان ژورنال: Stroke
سال: 2015
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.115.009252